Tiger Global Management slashed its valuation of e-cigarette startup Juul Labs Inc. to $19 billion, the latest sign of a broader reassessment investors are making of several one-time Silicon Valley darlings.

The write-down by one of Juul’s earliest boosters came at the end of September, according to people familiar with the matter. A Tiger Global spokeswoman declined to comment on the reason for the write-down.

Tiger…

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